Publications

2023
Benkafadar N, Sato MP, Ling AH, Janesick A, Scheibinger M, Jan TA, Heller S. An Essential Signaling Cascade for Auditory Hair Cell Regeneration. Dev Cell. 2023 Dec 20. PMID: 38128539.

TAD Evolutionary and functional characterization reveals diversity in mammalian TAD boundary properties and function. Nat Comm. 2023 Mar 7. Okhovat M, VanCampen J, Lima AC, Nevonen KA, Layman CE, Ward S, Herrera J, Stendahl AM, Yang R, Harshman L, Li W, Sheng RR, Mao Y, Fedorov L, Ndjamen B, Vigh-Conrad KA, Matthews IR, Easow SA, Chan DK, Jan TA, Eichler EE, Rugonyi S, Conrad DF, Ahituv N, Carbone L. PMID: 38062027.

2022
Single-cell transcriptomic atlas reveals increased regeneration in diseased human inner ears. bioRxiv. 2022 Oct 31. Wang T, Ling AH, Billings SE, Hosseini DK, Vaisbuch Y, Kim GS, Atkinson PJ, Sayyid ZN, Aaron KA, Wagh D, Pham N, Scheibinger M, Ishiyama A, Santa Maria P, Blevins NH, Jackler RK, Heller S, Lopez IA, Grillet N, Jan TA*, Cheng AG*. doi: https://doi.org/10.1101/2022.10.29.514378 (*corresponding authors)

RNA Sequencing and Gene Ontology Analysis in Acute Invasive Fungal Sinusitis. Am J Rhinol Allergy. 2022 Oct 26:19458924221134732. David AP, Loftus PA, Russell MS, Goldberg AN, El-Sayed IH, Jan TA, Roland LT. PMID: 36285477

Cell-type identity of the avian utricle. Cell Rep. 2022 Sep 27; 40(3):111432. Scheibinger M, Janesick A, Benkafadar N, Ellwanger DC, Jan TA, Heller S. PMID: 36170825.

Editorial: Otologic Trauma, Pathology, and Therapy. Front Cell Neurosci. 2022 Apr 13;16:900074. Landegger LD, Fujita T, Jan TA, Varela-Nieto I. PMID: 35496907.

2021
Spatiotemporal dynamics of inner ear sensory and non-sensory cells revealed by single-cell transcriptomics. Cell Rep. 2021 Jul 13;36(2):109358. Jan TA, Eltawil Y, Ling AH, Chen L, Ellwanger DC, Heller S, Cheng AG. PMID: 34260939.

Transcriptomic characterization of dying hair cells in the avian cochlea. Cell Rep. 2021 Mar 23; 34(12):108902.Benkafadar N, Janesick A, Scheibinger M, Ling AH, Jan TA, Heller S.  PMID: 33761357.

Greater epithelial ridge cells are the principal organoid-forming progenitor cells of the mouse cochlea. Cell Rep. 2021 Jan 19;34(3):108646. Kubota M, Scheibinger M, Jan TA, Heller S. PMID: 33472062.

2020
American Neurotology Society, American Otological Society, and American Academy of Otolaryngology - Head and Neck Foundation Guide to Enhance Otologic and Neurotologic Care During the COVID-19 Pandemic. Otol Neurotol. 2020 Aug 20. Kozin ED, Remenschneider AK, Blevins NH, Jan TA, Quesnel AM, Chari DA, Kesser BW, Weinstein JE, Ahsan SF, Telischi FF, Adunka OF, Weber P, Knoll RM, Coelho DH, Anne S, Franck KH, Marchioni D, Barker FG, Carter BS, Lustig LR, Bojrab DI, Bhansali SA, Westerberg BD, Lundy L, Jackler RK, Roland JT, Chandrasekhar SS, Antonelli PJ, Carey JP, Welling DB, Slattery WH, Lee DJ.  PMID: 32925832.

Cummings Otolaryngology: Head & Neck Surgery. Congenital malformations of the inner ear. 2020. Jan TA, Cheng AG, Jackler RK.

2019
The future of otology. J Laryngol Otol. 2019 Aug 29; 1-12. Jackler RK, Jan TA.  PMID: 31462337.

2017
Third-generation bisphosphonates for cochlear otosclerosis stabilizes sensorineural hearing loss in long-term follow-up. Laryngoscope Investig Otolaryngol. 2017 10; 2(5):262-268. Jan TA, Remenschneider AK, Halpin C, Seton M, McKenna MJ, Quesnel AM.  PMID: 29094069.

Pneumatocele of the Tympanic Membrane. Otol Neurotol. 2017 04; 38(4):e19-e20. Gadkaree SK, Jan TA, Quesnel AM.  PMID: 28198720.

Relationship between Surgically Treated Superior Canal Dehiscence Syndrome and Body Mass Index. Otolaryngol Head Neck Surg. 2017 04; 156(4):722-727. Jan TA, Cheng YS, Landegger LD, Lin BM, Srikanth P, Niesten ME, Lee DJ.  PMID: 28116976.

Operative Techniques in Otolaryngology-Head and Neck Surgery 28 (1), 11-16. Transcanal endoscopic tympanotomy. 2017; 28(1):11-16. Jan TA, Lee DJ.

2016
Improvement in word recognition following treatment failure for sudden sensorineural hearing loss. World J Otorhinolaryngol Head Neck Surg. 2016 Sep; 2(3):168-174. Jan TA, Kozin ED, Kanumuri VV, Sethi RK, Jung DH.  PMID: 29204563.

Profiling Specific Inner Ear Cell Types Using Cell Sorting Techniques. Methods Mol Biol. 2016; 1427:431-45. Jan TA, Jansson L, Atkinson PJ, Wang T, Cheng AG.  PMID: 27259940.

2014
Skin necrosis as a complication of therapeutic hypothermia. J Burn Care Res. 2014 May-Jun; 35(3):e184-6. Liu YM, Ibrahim A, Jan T, Chang P, Fagan S, Goverman J.  PMID: 24043239.

2013
Transient, afferent input-dependent, postnatal niche for neural progenitor cells in the cochlear nucleus. Proc Natl Acad Sci U S A. 2013 Aug 27; 110(35):14456-61. Volkenstein S, Oshima K, Sinkkonen ST, Corrales CE, Most SP, Chai R, Jan TA, van Amerongen R, Cheng AG, Heller S.  PMID: 23940359.

A simple method for purification of vestibular hair cells and non-sensory cells, and application for proteomic analysis. PLoS One. 2013; 8(6):e66026. Herget M, Scheibinger M, Guo Z, Jan TA, Adams CM, Cheng AG, Heller S.  PMID: 23750277.

Intranasal myiasis: a rare complication of transnasal skull base surgery. J Clin Neurosci. 2013 Aug; 20(8):1178-80. Jan TA, Redjal N, Walcott BP, Sheth SA.  PMID: 23669173.

Tympanic border cells are Wnt-responsive and can act as progenitors for postnatal mouse cochlear cells. Development. 2013 Mar; 140(6):1196-206. Jan TA, Chai R, Sayyid ZN, van Amerongen R, Xia A, Wang T, Sinkkonen ST, Zeng YA, Levin JR, Heller S, Nusse R, Cheng AG.  PMID: 23444352.

2012
Effect of obesity and medical comorbidities on outcomes after adjunct surgery for obstructive sleep apnea in cases of adenotonsillectomy failure. Arch Otolaryngol Head Neck Surg. 2012 Oct; 138(10):891-6. Chan DK, Jan TA, Koltai PJ.  PMID: 23069817.

Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea. Proc Natl Acad Sci U S A. 2012 May 22; 109(21):8167-72. Chai R, Kuo B, Wang T, Liaw EJ, Xia A, Jan TA, Liu Z, Taketo MM, Oghalai JS, Nusse R, Zuo J, Cheng AG.  PMID: 22562792.

2011
Isolating LacZ-expressing cells from mouse inner ear tissues using flow cytometry. J Vis Exp. 2011 Dec 23; (58):e3432. Jan TA, Chai R, Sayyid ZN, Cheng AG.  PMID: 22217925.

Intrinsic regenerative potential of murine cochlear supporting cells. Sci Rep. 2011; 1:26. Sinkkonen ST, Chai R, Jan TA, Hartman BH, Laske RD, Gahlen F, Sinkkonen W, Cheng AG, Oshima K, Heller S.  PMID: 22355545.

Dynamic expression of Lgr5, a Wnt target gene, in the developing and mature mouse cochlea. J Assoc Res Otolaryngol. 2011 Aug; 12(4):455-69. Chai R, Xia A, Wang T, Jan TA, Hayashi T, Bermingham-McDonogh O, Cheng AG.  PMID: 21472479.

Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells. J Clin Invest. 2011 Mar; 121(3):1217-21. Narsinh KH, Sun N, Sanchez-Freire V, Lee AS, Almeida P, Hu S, Jan T, Wilson KD, Leong D, Rosenberg J, Yao M, Robbins RC, Wu JC.  PMID: 21317531.

Effects of corticosteroids on functional recovery and neuron survival after facial nerve injury in mice. Arch Facial Plast Surg. 2011 Mar-Apr; 13(2):117-24. Lieberman DM, Jan TA, Ahmad SO, Most SP.  PMID: 21079107.

2008
Genetic analysis of tongue size and taste papillae number and size in recombinant inbred strains of mice. Chem Senses. 2008 Oct; 33(8):693-707. Reiner DJ, Jan TA, Boughter JD, Li CX, Lu L, Williams RW, Waters RS.  PMID: 18653645.

A functional role for Anopheles gambiae Arrestin1 in olfactory signal transduction. J Insect Physiol. 2008 Apr; 54(4):680-90. Walker WB, Smith EM, Jan T, Zwiebel LJ.  PMID: 18328499.

Genetic analysis of posterior medial barrel subfield (PMBSF) size in somatosensory cortex (SI) in recombinant inbred strains of mice. BMC Neurosci. 2008 Jan 07; 9:3. Jan TA, Lu L, Li CX, Williams RW, Waters RS.  PMID: 18179704.

2007
Early postnatal alcohol exposure reduced the size of vibrissal barrel field in rat somatosensory cortex (SI) but did not disrupt barrel field organization. Alcohol. 2007 Jun; 41(4):253-61. Oladehin A, Margret CP, Maier SE, Li CX, Jan TA, Chappell TD, Waters RS.  PMID: 17630086.

2006
Prenatal alcohol exposure (PAE) reduces the size of the forepaw representation in forepaw barrel subfield (FBS) cortex in neonatal rats: relationship between periphery and central representation. Exp Brain Res. 2006 Jul; 172(3):387-96. Margret CP, Chappell TD, Li CX, Jan TA, Matta SG, Elberger AJ, Waters RS.  PMID: 16424976.